  梅毒    螺旋体                                                  
                
     15             葡萄牙            雅司                                                 
         哥伦布                                            1492                     土著                                 1493             1497            
             
                            16                 1576                         15                      1497                1505               1510                  1506   1512                                    
          
             1905      Schaudinn  Hoffmann                                                                              12                         50           0     12    78                                    
        
           20                                           HIV      
                                          1964        20              
          
                                          （硬下疳）                                                                                  
                                                                              5            
          
       95 %                                                                                           4          
                     4                                  4                            
                               硬下疳              
                                                                        
         
                                  35                                                 
                                                                  
                                                                   
                                  1967 1986   20                  2939    71.6%   1839    72.6 %  40        22.7%   23.1%                             
           
                                                                                 （硬下疳）                                               
        
                                          24     530            48                                                                   24                                                            下疳                                                                                            
                                                   下疳                         （硬下疳    1015           
             （硬下疳）                                     13                                                      95100%                                                                                
                                                                                                2       34                                2                              
              
                       2                                                                       
               
                       3       10       90    32.5   
          硬下疳   90%                             (栗粒状)                                             1020                                                                        11.5cm                                                                        38                                 
            12                                                                                                         
                              13                                                  6090     
                                                                     
      5% 8%   37.538.5        玫瑰疹          39 40               
          10%                        
                                            
                             
                                                                                                                  
                                                                                                                                        
                                              
                                   12                                                 
              
               0.51                     2      34          510      40%                                                   
                   28.4%        310                                 